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We demonstrated that in yeast limited in calorie supply the atg32Δ-dependent mutational block of macromitophagy reduces mitochondrial respiration, decreases capacity of the mitochondrial ETC, lowers the efficacy of coupling between ADP phosphorylation and electron transport, and disproportionally lessens activities of all OXPHOS enzymes.
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Jasmin's team lessened activity in the RAIC of rats by injecting a drug that blocks the enzyme that digests g-aminobutyric acid (GABA), a common neurotransmitter, thus raising GABA levels.
This lessens the activity needed for feeding, resulting in weight gain.
Azathioprine is an immunosuppressant medication that lessens the activity of the immune system.
Of course, latent EBV infection may exert a supportive role for the NF- κB pathway and might lessen its activity without altering basal cell growth activity in both sublines.
Corticosteroids are medications that reduce inflammation and lessen the activity of an over active immune system.
This reduced risk for hypoglycemia, as well as a reduction in the need for twice-daily injections, has been attributed to the prolongation of action by retarding subcutaneous absorption, lessening peak activity, and reducing variability of circulating insulin levels.
Early observations in patients with active RA suggest a tendency toward lessening disease activity in pregnancy.
"I would expect it to continue at least through mid-June, when the kids are out of school and we usually see a lessening of activity".
Every practice of heartfulness strengthens heart awareness while lessening mental activity.
Indeed it has been reported that binding of TPI to an yet unidentified component of red cell membranes can lessen the activity of TPI [23].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com