Sentence examples for lessen the toxicity from inspiring English sources

The advent of targeted applications of immune-based therapies offers children with cancer a new class of oncolytic therapies that may be used to treat disease refractory to conventional approaches and lessen the toxicity of current treatment regimens without compromising remission.

Despite this activity, there is a pressing need to develop new regimens to improve the response and lessen the toxicity of treatment, thereby optimising quality of life in these patients treated with palliative intent.

The primary step for inhibitor detoxification in A. resinae ZN1 is the fast degradation of furfural or HMF into the corresponding furfuryl alcohol or HMF alcohol to lessen the toxicity on its growth and metabolism [ 25, 26].

Furthermore, we believe that our practice of limiting the use of FOLFIRINOX to patients who had adequate biliary drainage also helped to lessen the toxicities since irinotecan depends on biliary elimination.

ArsH protein may play an important role in lessening the toxicity of arsenite.

The expression of arsC, arsB, and arsR under pure culture and coculture was consistently upregulated upon shock after 30 min, lessening the toxicity toward At.

Put colloquially, the recommendations are making the best of a bad job"..Rebranding a problem – in this case, LiPs who are now called "self-represented litigants" – is a typical politician's semantic sleight of hand to lessen the perceived toxicity of an issue.

These PLGA-PEG-Apt nanoparticles can boost the therapeutic effect of anticancer drugs and lessen the systemic toxicity when compared to non-targeted nanoparticles.

FDA and more recent EULAR dosing guidelines for allopurinol have suggested the use of reduced doses in renal failure in order to lessen the risk of drug toxicity [ 6, 35].

Limited dose oral colchcine regimens of this type, particularly if started within the first 24 hours of the gout flare, are useful because they can lessen the frequency of gastrointestinal toxicity, which sometimes is severe.

The introduction of cyclophosphamide and glucocorticoids brought about the potential for long-term survival and provided the opportunity and impetus to explore treatment options that can reduce the toxicity of therapy and lessen the likelihood of relapse.