Unless we had some reason to think that such functions really did describe the world, we might well feel that a solution was less than imperative and less than unique.
This is admittedly a very conservative benchmarking strategy, as neighbouring contacts clearly have at least some additional value in constraining the chain fold, but their value is clearly much less than unique long range contacts that are correctly predicted.
Our observation that tandem poly(A) sites are generally less conserved than unique sites suggests that most novel sites are quickly lost and therefore are either neutral or deleterious.
For robust evaluation of transcript expression level, we eliminated 1101 transcripts that were targeted by less than three unique probes, and we used 508,908 unique probes of 43,934 transcripts in this study (Additional file 26: Table S15).
A positive window was considered to contain no less than 10 unique reads, with more than half of the unique reads being 21 nt in length and with no less than three 21-nt unique reads falling into the phase registers.
Chromosomes 4, 5, 7, 8, 9, and 11 carried the highest number of SNPs (more than 350,000 unique SNPs per chromosome) and very few SNPs were detected on chromosomes 1, 6, and 10 (less than 150,000 unique SNPs).
Areas with zero happiness score and areas containing less than ten unique users were discarded.
TechMeme is too small to be counted by Comscore, so they probably had less than 500,000 unique visitors.
We aggregated the calls' weights between cells during this week, then filtered out edges in which the calling/called cells were discarded in a previous stage (either because they had less than ten unique Twitter users or because they had zero happiness score).
True to their age-old style, each song, new and old, had less than five unique lines.
Up to now, less than 200 unique membrane protein structures have been deposited in the PDB compared to thousands of soluble proteins.
