Sentence examples for less sequencing depth from inspiring English sources
These features make MICC superior over other existing tools especially when processing ChIA-PET data with less sequencing depth.
Considering studies on other protists, which were able to cover most of the annotated genes with less sequencing depth, the former seems unlikely [ 53– 53].
Messenger RNA-Seq (mRNA-Seq) is based on poly(A) capture, thereby requiring less sequencing depth, and will reflect more faithfully the coding transcriptome, although it will not account for coding transcripts that are not poly-adenylated [ 80, 81].
Because metatranscriptomics targets only the transcribed elements of each genome, the resulting data set is less complex, and requires less sequencing depth in order to achieve the same level of coverage compared to a metagenome.
The disparity might be due to less Chinese participant enrollment, fewer sampling sites in each habitat, different sequencing targets, and less sequencing depths in our study.
This method showed to be less demanding in terms of sequencing depth and multiple libraries construction compared to a complete de novo assembly.
Furthermore, sequencing of barcoded libraries through Illumina Hi-Seq 2500 ensures fast turn-around time (less than 48 hours) and good sequencing depth (~160 million reads per lane) at a relatively low cost.
Compared with other next-generation sequencing technology, such as Roche 454 technology, the Illumina solexa platform offers a higher sequencing depth with considerably less cost, which ensures more complete coverage of the transcriptome.
After the amplification round, several over-amplified clones fill most of the sequencing capacity, while less popular clones become undetectable at given sequencing depth.
In spite of tremendous efforts in these previous studies, the sequencing depth was still significantly less than predicted total diversity and one might argue that additional sequencing would reveal homogeneous communities along these gradients.
Improvement is also observed, although less significant, for the dataset with 20× sequencing depth (which can already be assembled fairly well by SOAPdenovo with a gene coverage for all genes in contigs of 81%).
