Less CpG sites will lead to much more segments but reduce the complexity of the variations while more CpG sites will reflect much more complexity of pattern variations but will leads to less segments since the minimum requirement of read coverage to cover all the possible combinations of DNA methylation states will be high (e.g. for a five-CpG segment, we may have to require 2^5 = 32 reads).
Additionally, it contains one of the most obtuse gay coming-out scenes in film history - presumably in the hope that the less progressive segments of the audience will miss it altogether.
"The Girl From the Coast" takes place at the beginning of the 20th century, when the Dutch colonial government allied itself with the Javanese feudal aristocracy to suppress less powerful segments of the population.
The protest movement defiantly encamped in Bangkok began as a reaction to Mr. Thaksin's ouster, but it has expanded into a social movement as less affluent segments of Thai society rebel against what they say is an elite group that tries to control Thailand's democratic institutions.
The company has its hand in the less saturated segments of the market, such as the enterprise market, service providers, and optical and wireless infrastructure.
However, from 2003 onward, opposition to FGM started to spread from the better educated and less traditional segments of society to almost all segments of Egyptian society.
In fact, the less polluted segments of the JT walking path had PM2.5 and PM10 values that were similar to the average for all of EL.
Several studies show trends of a higher prevalence of cleft lip/palate in lower social classes, and some have reported cardiovascular anomalies, genitourinary anomalies, polydactyly, syndactyly, limb reduction defects and hydrocephalus to be more frequent in less privileged segments of the population.
On the contrary, if the latter is indeed a priority in the health policy agenda, online information on healthcare providers should be seen as a challenging opportunity to enhance patients' choice in healthcare, and public engagement with health information, especially for the less favoured segments of the population.
Also, since communication needs and preferences differ by many factors, we should reflect upon the need for, but also the feasibility of, audience segment-specific data versus the generalizability of less segmented data.
