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After 48 hours, more then half of the T cells incubated with KbWT-DCs had proliferated and although less proliferation was detected still a considerable fraction of T cells incubated with Δ7-DCs were dividing.
CREBBP mutant B cells stimulated less proliferation of T cells in vitro compared with wild-type B cells from the same tumor.
Reduced overgrowth could have been caused by less proliferation or more cell death; our data from wing discs suggested that cell death was likely to be occurring7.
In accordance, in mixed lymphocyte reaction, DnaK-pre-treated BMDCs provoked less proliferation of CD4+ and CD8+ T cells compared with those co-cultured with non-treated BMDCs (Fig. 7f).
SPTs undergo less proliferation in a mixed lymphocyte reaction (MLR) when compared with unpulsed Tregs, suggesting that Treg-mediated suppression may be inversely related to their proliferative capacity.
They are manufactured in a completely encased unit, including the nuclear fuel, so there is more security in the nuclear fuel cycle and less proliferation risk.
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The six also seek to re-engineer Arak from a model that produces enough plutonium for several nuclear weapons a year to a less proliferation-prone model.
The six have promised Iran assistance with other, less proliferation-prone nuclear technology, and direct talks on a whole range of economic, trade and security issues that Iran itself raised in a set of counter-proposals last month.
A 1994 deal negotiated by America that froze North Korea's plutonium production in return for oil deliveries and the building of two less proliferation-prone nuclear reactors hangs by a thread.
Neither the offer of inducements trade and political talks, including with America, and help with less proliferation-prone nuclear technologies are all on the table nor the threat of further sanctions seems to give Iran pause.
It has brushed off offers by the six countries of wide-ranging economic and political inducements, including co-operation in less proliferation-prone nuclear technologies, once it stops enrichment.
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