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Certainly it has much less obvious impact than a film with a similar driver-passenger theme: Kiarostami's Palme d'Or-winning Taste of Cherry.
Outgoing Fifa president Sepp Blatter last year suggested coaches could have a limited number of challenges available where they could interrupt play and request a video review, but MLS and others seeking to implement video replay want a behind-the-scenes approach that will have a less obvious impact on the game.
But this most fanciful and surreal of Williams's dramas has definitely had a far-reaching if less obvious impact, and "Once" quotes the playwrights John Guare and Richard Foreman on its particular influence on them and on the avant-garde theater in general.
The deletions in the VP1 BC loop had a less obvious impact on HEV receptor footprints which were mostly located on the β-sheets rather than the loop (Figure 4).
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Finnish samples have been extensively utilized in studying single-gene disorders, where the founder effect has clearly aided in discovery, and more recently in genome-wide association studies of complex traits, where the founder effect has had less obvious impacts.
Making it a harbinger foretelling some of the less obvious impacts coming from the battle over this bottom of the barrel petroleum currently being foisted on the world by the oil industry.
However, injury can also have less obvious impacts.
Public attention tends to focus on the more visible signs of agriculture's impact on the environment, whereas it seems likely that the non-visible or less obvious impacts of air pollution cause the greatest economic costs (Pretty et al., 2001).
In the meantime, the company set up a similar site on a beach in Sierra Leone, and now here in Italy, which is a bit of a departure – less remote, less adventurous, and with a less obvious social impact.
The significant influence of CDR H2 on antigen binding was via direct interaction with antigen and also via the less obvious indirect impact on the orientation and corresponding pocket shape and size delivered by the positioning of CDRs H3 and L3.
The example presented here of how climate change could affect the supply of blood in Australia by extending the range of dengue-favourable environments illustrates what should be a global concern, and highlights the importance of considering what may be a less obvious climate impact on health.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com