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Extended meropenem infusion was also not associated with less emergence of resistance compared with intermittent infusion.
However, in a randomized trial among ICU patients with severe sepsis, a combination of meropenem and moxifloxacin was associated to less emergence of resistance at the infection site to meropenem and aminoglycosides than meropenem alone [ 56].
A multicentre randomised controlled trial indicated similar clinical efficacy for 8 versus 15 days of antibiotic therapy for VAP, with less emergence of multiresistant organisms following the shorter course [ 1].
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On the other hand, a less synchronized emergence of O. rimosa (in comparison to the periodical cicadas) and a corresponding slow increase in singing probability might deplete the parasitoid of its larvae and ensure reproduction of the cicada.
Double mutation happens less frequently; emergence of the M184V mutation is less frequent with Tenofovir/Emtricitabine than with Zidovudine/Lamivudine, while selection of the Lamivudine-associated M184V mutation to the Zidovudine/Lamivudine combination has been associated with increased susceptibility to Zidovudine [ 37].
A diary she began keeping at age 15, if read, might have made her emergence less shocking.
And while the choice of territory may have made pragmatic sense at the time (that of language less so), the emergence of the Zionist movement could not help heightening rather than attenuating the religious underpinnings of the Jewish nation.
None the less, the sudden emergence of the Floridian means Idowu will have two 21-year-olds pushing the 18m mark to contend with in London next year, presuming the Frenchman Teddy Tamgho recovers from his broken ankle.
Compared to their emergence, less attention has been paid to the details of survival and development of established small trees in uneven-aged stands in the area.
The T-cell repertoire in patients with RA is markedly contracted, with less diversity and emergence of dominant T-cell clonotypes [ 39].
Given the positive-feedback dynamics of intron proliferation, it could be quite rapid, conceivably requiring less time than emergence of an RNA-coating protein (complex) which would need to distinguish mRNAs from non-coding functional RNAs in the cell.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com