In naive human immunodeficient virus (HIV -infected patients, emtricitabine was more efficacious tHIV -infected but less efficacious than lamivudine; in expatientsd patiemtricitabineine and stavudine had equal efficacy.
Three hours after antisepsis, the bacterial reduction on the gloved hand was only significantly less efficacious than that of the reference when 75% ethanol was used.
Vaccine efficacy of AdPvs25 was slightly higher than to a recombinant Pvs25 protein mixed with aluminum hydroxide, but less efficacious than the protein emulsified with incomplete Freund's adjuvant.
Although previous studies have found automated percutaneous discectomy and epidural percutaneous discectomy to be less efficacious than conventional discectomy, these percutaneous procedures may be effective and cost-effective as a first surgical treatment for herniated lumbar disc.
Assuming that crystalloid solutions possess glycocalyx releasing properties per se, and given the fact that crystalloids were less efficacious than the colloids to restore blood pressure, we cannot exclude that the amount of heparan sulphate and syndecan-1 would have been higher in the RA group if resuscitation had been targeted to obtain similar blood pressures in all groups.
In the case of off-label medications, the assumption of equal efficacy with rectal diazepam was a conservative estimate as clinical experts in several countries suggested that other off-label medications, such as lorazepam tablets administered by the buccal route, were less efficacious than rectal diazepam.
The semi-quantitative findings indicated that Cpd α is slightly less efficacious than TCBZ itself in causing histological damage to the reproductive structures of TCBZ-sensitive flukes, and that, like TCBZ, it caused no histological damage in flukes of the TCBZ-resistant isolate.
Although entacapone is relatively safer, it appears less efficacious than tolcapone [6] [8].
Chloroquine (CQ) plus SP has been less efficacious than AQ+SP in trials in Africa owing to widespread CQ resistance.
In clinical trials, pharmacological inhibitors of PDE4 developed as potential therapies for treatment of inflammatory diseases were less efficacious than preclinical data suggested [18], [21], [22]; consequently, none has yet been approved for clinical use [23], [24].
It also stresses the added value of pre-pandemic vaccination, which can be used immediately, even if less efficacious than the appropriate pandemic vaccine which may take several months to be produced and distributed.
