Sentence examples for less differentiated with from inspiring English sources

Bladders exposed to intravesical MNU develop progressive neoplastic changes, with the lesions becoming progressively less differentiated with time, developing from CIS through to papillary carcinoma and finally resulting in large bulky muscle-invasive tumours, which have a relatively low potential for metastasis (Kunze et al., 1976).

Therefore, understanding was poorer in the group of children and adolescents with the ADHD combined with ODD and their answers were less differentiated compared with the group of patients with ADHD alone.

This GEM model develops prostatic intraepithelial neoplasia (PIN), followed by invasive gland-forming PCa and invasive and metastatic less differentiated PCa, with neuroendocrine (NE) differentiation (NE Ca).

One study has taken advantage of the correlation between pigmentation and differentiation of melanoma cells: less differentiated cells with a low level of pigmentation (resembling an EMT-like state) were migratory at the primary site and they intravasated, whereas differentiated and pigmented cells did not.

The term 'dedifferentiation' has been reported as a progression of cells towards a less differentiated state with no longer the original line of differentiation (Dahlin and Beabout, 1971).

Dahlin and Beabout (1971) reported the term 'dedifferentiation', which is the progression of cells towards a less differentiated state with no longer the original line of differentiation.

Instead Renault turned out less differentiated vehicles with a strong emphasis on value for money.

Concomitant down regulation of Let-7 and augmented HMGA2 expression results in less differentiated tumours with stem cell-like characteristics [6], [9], [13], [14], [15].

However, there is some evidence that less differentiated cells with stem cell characteristics are present among aspirated follicular cells (AFCs).

It is uncertain why larger and less differentiated tumors with more SCNA were diagnosed at later age.

The present ultrastructural findings support these suggested roles since MYCN amplified cells had a morphologically less differentiated appearance, with associated morphometric changes.