Sentence examples for less constrained regions from inspiring English sources

Altogether, these findings support a model in which genes can preferentially harbour introns in less constrained regions of the protein fold they code for.

For example, we expect that less constrained regions should exhibit relatively fast HDX, whereas structured and buried regions exchange slowly.

This observation is in line with the well-established concept that evolutionarily divergent regions exhibit higher intraspecific variability; the link between both levels of variability is given by the degree of functional constraints (less constrained regions evolve faster and have higher polymorphism levels, see for instance Tajima, 1989).

It consists in the recrystallization of whole lamellar stacks to give a state of overall lower free energy, with much thicker and dense crystals separated by larger and less constrained amorphous regions of lower Tg.

This could explain their lower polymorphism compared to other loci located in less constrained intergenic regions Multilocus level analyses revealed no redundancy within the collection, so we used all the individuals for further analyses.

Only the less constrained terminal regions gave significant chemical shift effects in CEST experiments, therefore, we could not obtain detailed structural data on the low-populated hidden state and can only provide a highly approximate structural model based solely on moderately informative N chemical shifts (see the Supporting Information, Figure S47 and Table S5).

In a study of five Plasmodium species we noted that Plasmodium transcription factors and parasite lifestyle-associated genes might behave similarly as they have less constrained coding regions (higher dN/dS or rates of nonsynonymous substitutions per nonsynonymous site to synonymous substitutions per synonymous site) than other groups of genes [ 30].

A negative correlation is expected if slightly deleterious mutations, and possibly also genes that are less constrained, accumulate in regions of the genome with low recombination frequency because of the reduced efficiency of natural selection.

Each nrDNA copy is organized into less constrained ITS1 and ITS2 regions separated by the 163 164 base pair 5.8S region, which is highly conserved when functional copies are compared within genera or between recently diverged genera [ 42, 56].

A constrained device may delegate its heavy cryptographic load to less constrained nodes in neighborhood exploiting the spatial heterogeneity of IoT environment.

For footprinting to be efficient, overall sequence conservation between two species needs to be high enough to maintain regulatory sequences, but low enough to allow evolutionary sequence modification of less-constrained DNA regions.