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This agent has less adverse effect on metabolic parameters than other diuretics (45, 46), is more effective than enalapril in reducing left ventricular mass (47), is equivalent to enalapril in reducing microalbuminuria (48), and is effective in reducing CV morbidity and mortality in clinical trials (3, 9, 16, 49).
Notably, complex 9 effectively inhibited tumor growth in the NCI-H460 xenograft mouse model with less adverse effect than cisplatin.
Optimum levels of fiber contents for spalling protection with a less adverse effect on workability are provided based on the results of the fire test by varying the NY and PP fiber content.
Despite the complex molecular etiology of SLE, corticosteroids are commonly used to treat most of the SLE patients but long term usage of these drugs may induce numerous side effects, urging a need to develop more target- or mechanism-based therapy with less adverse effect.
Taken together, our treatment modality may provide a more beneficial treatment outcome with less adverse effect.
How to enhance the mass transfer with less adverse effect is considered as one of the important bioengineering issues.
Similar(46)
Hence smaller amounts of colesevelam can be used effectively, with less adverse effects, and with greater tolerability through its packaging into tablets instead of a slurry of liquefied powder.
Eperisone intervention may be effective in acute LBP patients with less adverse effects (relative risk, 0.25; 95% confidence interval, 0.15 0.41; p < 0.0001).
This would lead to a more effective inhibition of the inflammatory diseases with less adverse effects.
It is a nonopioid analgesic as effective as morphine, tramadol, and meperidine and produces less adverse effects than others [ 4].
Compared with the slow acetylators, the drug is less effective in this latter group, and this group probably has less adverse effects.
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