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The most prominent lesion was extensive inflammation of the heart, consisted of lymphocytes, macrophages, numerous multinucleated giant cells, and occasional heterophils.
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Since the lesion is extensive, an associated periosteal reaction is seen (arrowhead) Open image in new window Fig. 24 Diagram of a classic metaphyseal lesion depicts a "corner" incomplete fracture (left) and a "bucket-handle" complete fracture (right).
There may, however, be a risk of associated microinvasive foci, especially when the lesion is extensive (McMasters et al, 2002; Moran et al, 2005; Tunon de Lara et al, 2008).
Thirty-nine (31.5%) lesions were extensive (involving ≥3 TDLU) and 85 (68.5%) were focal (involving ≤2 TDLU); 82 (66.1%) lesions were found incidentally, and 42 (33.9%) were targeted.
DCIS may necessitate mastectomy when the lesions are extensive, multi-centric or recurrent, however, sometimes patients request to be managed in this way.
In the remaining rats (n = 9), the perirhinal cortex lesions were extensive and removed almost all of the target region (see Figure 3).
In the remaining animals (n = 9), the perirhinal cortex lesions were extensive, sometimes removing all of the target region (see Figure 2).
> -wrap-foot> In the individuals with left ventral damage (EL and GB), the lesions were extensive, whereas in the patients with right ventral damage, the lesions varied both in size (SM small, EC extensive, and CR scattered) and location.
The relative lesion burden for each lung lobe from individual mice was determined by scoring (0-5 points) using the following scale: 0=no lesions, 1=focal lesion, 2=multiple focal lesions, 3=one or more focal severe lesions, 4=multiple focal lesions that are extensive and coalesce, and 5=extensive lesions that occupy the majority of the lung lobe.
Surgery was not pursued, as the lesion was so extensive that the required surgery would cause too great a neurologic deficit.
The spinal cord lesion of this dog was extensive, affecting a large proportion of both white and grey matter, making recovery very unlikely.
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