Sentence examples for lens terminal from inspiring English sources

DNase IIβ is an enzyme critical for lens terminal differentiation [77], [78].

The highest concentrations of FGF2 induce cellular elongation and other attributes of lens terminal differentiation, including the accumulation of crystallins and the degradation of subcellular organelles.

In transgenic lenses, a large number of primary lens fiber cell nuclei were found scattered across the lens equator, which might indicate a delay of lens terminal differentiation in the transgenic embryos (compare Figures 3E and 3G with Figures 3F and 3H).

These results provide new molecular insights into the process of lens fiber terminal differentiation and open new research avenues to probe chromatin structure prior to and during lens fiber cell denucleation.

Interruption of normal lens cell terminal differentiation is hypothesized to be the cause of posterior subcapsular cataracts (PSCs), a type of age-related cataract that is especially common in diabetics and in patients receiving immunosuppressive steroids or therapeutic radiation.

In contrast, Hsf4 regulates lens fiber cell terminal differentiation [ 49].

Our results demonstrate that lens fiber cell terminal differentiation, including their denucleation (karyolysis), requires the ATP-dependent chromatin remodeling enzyme Brg1.

These studies demonstrate a cell-autonomous role for Brg1 in lens fiber cell terminal differentiation and identified DNase IIβ as a potential direct target of SWI/SNF complexes.

This observation was confirmed in our observations of E18 wild-type mouse lenses, using the terminal deoxynucleotidyl transferase (TdT -mediated dUTdT -mediatedabelling (TUNEL) reaction (see MethodUTP

These results demonstrate that Dicer1, and, inferring from it, miRNAs, are required for survival of the lens epithelium and for terminal differentiation of lens fiber cells.

DNase 2b, also known as DNase 2-like acid DNase, DLAD, is specifically expressed in the eye and degrades nuclear DNA in the course of terminal differentiation of lens fiber cells [20].