We found that small cortical and cuneiform opacities are accompanied by changes in fiber structure and architecture mainly in the equatorial border zone between the lens nucleus and cortex.
To assess the frequency of pseudoexfoliation syndrome (PXF) in patients scheduled for cataract surgery and to evaluate its association with pupil dilation, lens nucleus hardness, intraocular pressure (IOP), glaucoma, age, and sex.
In principle, each of the lens structures (cortex, nucleus, embryonic lens nucleus) can become opaque and therefore cause a cataract.
In those studies, the concentrations of phospholipids were the highest at the cortex of the lens and decreased toward the lens nucleus.
The oldest cells are positioned in the innermost segment of the lens (nucleus), whereas the younger cells are located in the cortical region (cortex) of the lens.
As we have previously shown, this trend occurs with all but one identified SM [9] and suggests that these lipids play a functional role in the lens nucleus by providing stiffer membranes that are more resistant to various stress factors.
Our results allow us to conclude that the crystalline formation in the lens nucleus almost entirely takes place around the time of birth, with a very small, and decreasing, continuous formation throughout life.
We elucidated the spatial distribution of sphingolipids in the porcine lens using MALDI MSI and provided detailed information about compositional changes in the clear lens nucleus and cortex [9].
In conclusion, our results show that the aged human donor lenses can regain the colour of younger lenses by being treated with subtle low-energy infrared femtosecond laser pulses that evoke two-photon events in a target volume inside the intact lens nucleus.
Phacoemulsification of the lens nucleus was performed.
The lens nucleus and cortex were hydrodissected with BSS.
