Exact(8)
This interaction demonstrated differential activity in the left insula (BA13) (x = −41 y = −4 z = 10) at a more lenient threshold (p<0.01) (Figure 3a).
The contrast intrinsic intra-item binding did not reveal any significant activation, even at a very lenient threshold of p<0.1.
The implications of using this lenient threshold depend on what result is being considered and are described in each case below.
Also, based on anatomical pre-defined hypotheses (frontopolar cortex and medial temporal lobe (MTL)) as well as low number of subjects and events (predictive of low statistical power), we also used the lenient threshold of p<.005.
Although the activity of the intraparietal sulcus was revealed at a lenient threshold and would thus need further investigation, its function of information accumulation would fit well within the present construct of PM.
All three methods indicate a stronger LSMA/LSMC correlation during right hand movement, and a stronger LSMA/RSMC correlation during left hand movement, based on the 90% confidence intervals (though these comparisons will show some false positives because of the lenient threshold and number of tests).
Interestingly, this was the only time point of the task where a frontopolar (BA 10) area was detected, however at a lenient threshold, which needs to be confirmed with other experiments (see Fig. 3C and Table S2, contrast between Switching and End events).
A more lenient threshold also revealed increased putamen activation.
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