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Low age, low BE, male gender, high ISS and lengthened time from injury are unique predictors for low fibrinogen concentrations.
Low age, male gender, lengthened time from injury, low base excess and high ISS were unique contributors to low fibrinogen concentrations on arrival.
Furthermore, sepsis was more prevalent in patients with AKI (P < 0.0001) and these patients had lengthened time of hospitalization (P < 0.0001), as compared with patients with no acute renal impairment.
Low general health service utilisation for acute or long term conditions lengthened time to cancer symptom presentation [ 9, 34, 42, 43, 57, 58, 61, 66, 68, 73, 77, 78, 80, 84].
The findings of the current review confirm that failure to appreciate the seriousness of symptoms [ 6, 16] and non-disclosure of symptoms [ 6, 15] lengthened time to symptom presentation.
One explanation for this association may be the lengthened time frame for the increased consumptive process of fibrinogen previously described in animal studies, regardless of hypothermia and acidosis [ 6, 33].
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