Sentence examples for length slippage from inspiring English sources
Equally, round length slippage results in some interval cancers occurring more than 36 months after a woman's last screen and may inflate rates of screen-detected cancers.
Linking screening service and cancer registry data to enable individual follow-up to be estimated allows interval cancer rates to be calculated per woman years instead of per women screened and takes account of early re-screening/round length slippage and loss to follow-up; however this process is labour intensive (Fracheboud et al, 1999).
However, it is substantially higher than the value obtained by Dieringer and Schlötterer (2003) (3 repeats), who proposed the threshold as a boundary between length-independent and length-dependent slippage at low and high repeat numbers, respectively.
More importantly, we detected no lower threshold length for slippage.
In this study, we used mammalian DNA polymerase β (pol β) as a model to test the relationship between tandem repeat allele length and slippage-induced mutational dynamics, for several reasons.
For example, the issue of a minimum threshold length for DNA slippage remains contentious.
The microsatellite with longer repeat-motifs is expected to be more polymorphic due to high length dependent replication slippage [ 27].
The issue of the minimal threshold length for DNA slippage thus remains open, with conclusions mainly depending on the investigation method.
The existence of a threshold length for DNA slippage has essentially been inferred from model-fitting methods (Rose and Falush 1998; Sibly et al. 2001; Dieringer and Schlötterer 2003; Lai and Sun 2003).
Here, we address the question of a minimal threshold length for DNA slippage based on a comparative analysis of the whole human and chimpanzee genomes, therefore significantly expanding the number of loci over previous studies.
The microsatellites with longer repeat motifs have a tendency to be more polymorphic due to their high length-dependent replication slippage.
