The requirement of arms-length recruitment of practices through Divisions of General Practice contributed significantly to the difficulties of recruiting general practices and retaining them throughout the trial.
No one needs to know that they're sitting through a feature-length recruitment film.
The University of New South Wales Human Research Ethics Committee approval required arms-length recruitment of both practices and, in particular, patients.
The length of recruitment was 3 weeks for the Scott & White Memorial Hospital and 6 weeks for the Christus St. Elizabeth's Hospital.
The study interviews were 20 to 25 minutes in length, hindering recruitment, but allowing us to collect a larger amount of detailed data from a smaller sample.
The length of recruitment period of half a year and the restriction to one medical centre were chosen because the estimated number of 350 new consecutive patients would be sufficient to provide input for an inventory study.
So provided it could actually be nested within and wasn't really pushing the boundaries of the inclusion or exclusion criteria, or the length of recruitment, provided then it wasn't going to scupper the trial it's nested in.
The major practical problem associated with this conventional design is its requirement of a sufficiently large sample size to power each of the multiple trials to a designated level (eg, a power of 80%) and, hence, an increased length of recruitment and cost.
We report a small simulation study comparing the significance level and power of the logrank and RMST tests under a piecewise exponential model with non-proportional or proportional hazards, incorporating staggered entry of patients and varying length of recruitment and follow-up.
Only 8 reads (2.3 × 10-4% of genome length-corrected recruitments) were recruited with high fidelity to the genome of Mycobacterium tuberculosis, the causative agent of tuberculosis, a disease that is common in the Northern Cape region of South Africa [ 39].
