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The difference in robustness can range from a few percent to fifty percent or more, depending on the length of the pathway and on the metabolite one considers.
As exponent α increases from 1.001 to 6, the dominant sub-network becomes denser, and the length of the pathway becomes longer.
We fix the length of the pathway at n = 5genes.
We varied the length of the pathway to study the effect of this parameter on the model behaviour.
This was supported by the fact that the phloem phase of M. persicae on SKS13 overexpressing plants was delayed in time and reduced in length, while the length of the pathway phase was not significantly different from the control.
A single pathway was chosen from this pool on the basis of minimizing the length of the pathway, minimizing the number of unknown enzymatic steps, and predicting the thermodynamic likelihood of each reaction.
Similar(54)
Differences in the length of the pathways between substrate (in this case, glucose and acetate) and the storage compound synthesized may suggest differences between metabolic optimality for the different compounds with respect to the mixture of storage compounds accumulated.
These values were further multiplied by the mean length of the pathways connecting each seed with each target voxel [Beckmann et al., 2009; Eickhoff et al., 2010; Tomassini et al., 2007] to ensure that the results of tractography, and the following calculation of similarity between connectivity maps, were not biased toward nearby connections due to the mere anatomical proximity.
Specifically, (1) we corrected the count of the samples in each target voxel by the mean length of the pathways connecting each seed with each target voxel to ensure that the results of tractography would have not been biased toward anatomically close target voxels.
A pathway is a graph P, where V(P ={x0, x1,…, xK} and E(P ={x0x1, x1x2, …, xK−1xK}, K denotes the number of edges in E(P) defined as the length of this pathway.
Given the shorter length of the DXP pathway, initial experimental testing focused on the seven genes of the DXP pathway.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com