The protocol specified that 10 minute sessions should occur daily; however, since the paper logs did not include the length of treatment, adherence recorded by the devices was defined as the number of sessions initiated relative to the number of possible sessions.
A broad range of patient safety and clinical effectiveness outcomes including mortality, physical symptoms, length of stay and adherence to treatment.
Further, the efficacy of the implementation intervention had to be reported in terms of a clearly defined outcome such as mortality, length of stay, and/or adherence to delirium screening.
While the available studies have flaws, they do suggest that ED invasive lines are a source of infection, remain in place for a substantial length of time, and that adherence to maximum barrier precautions is poor.
Number randomized, superiority of treatment versus control (Hedges g) on primary outcome measure, risk of bias, length of follow up, patient adherence and satisfaction were extracted.
Results of the meta-analysis of the 22 studies [22] [43] are displayed in Table 1: grouped by diagnosis, listing author and date of publication, N randomized, effect size of intervention compared to control condition (Hedges g), NNT, risk of bias; length of follow-up; and adherence and patient satisfaction as a proxy for acceptability.
Implementation results showed a decrease in time to functional recovery, a decrease in hospital length of stay and increased adherence to the ERAS programme elements [ 22].
We will also calculate overall ribavirin exposure, which will take into account three factors: percent of prescribed doses taken (adherence), length of time on treatment (persistence), and proportion of the original dose taken (dose reduction) [ 24].
The outcome measures specified for consideration were venous transit time, blood flow/velocity, incidence of PTS, DVT, PE and/or VTE, patient adherence, length of hospital stay and device-related adverse events.
