From day 6, spectratyping analysis revealed that the Vβ13+ compartment became restricted to a CDR3 length correlating to 14 amino acids ( Fig. 4B ), suggesting that either a single T-cell clone or only a limited number of clones in the Vβ13 compartment had expanded.
Our data shows that telomere length directly correlates to the length of the chromosome arm.
In each case, flanking sequences were obtained up to a maximum length (correlating to the median size of the IGR as indicated in Additional file 1: Table S1) unless the adjacent ORF was encountered, in which case, only the flanking sequence up to the ORF was taken.
In addition telomere length highly correlates to aging, and telomeres might be more vulnerable in old age and then contribute to AD development.
In general, step length correlates negatively to step frequency [ 60], but in elite athletes step length appears to exert a larger impact on sprint performance [ 61].
In consistence, cerebellum telomere length correlates inversely to age in AD patients (Lukens et al., 2009).
In fact, the length of ROH inversely correlates to the distance in the pedigree where a common ancestor is present [ 14], which makes it a powerful method to detect inbreeding effects [ 15].
This is consistent with the finding that fibril length correlates with the ability to disrupt membranes and to reduce cell viability for a number of amyloidogenic proteins [51].
It is likely that telomere damage due to, for example, persistent oxidative stress in the long run will lead also to a decrease in mean telomere length, which can explain why mean telomere length correlates with both distance to lesion and parallel Mankin score.
Studies in telomerase-minus mice have suggested that telomere length correlates with organismal sensitivity to radiation [26], [27].
