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Moreover, HIPK2-null mice are characterized by head and snout crushed, a curvature of the spine, and distortion of the front and rear legs (data not shown).
Importantly, although both nan 36a and 5-40 Leg >TNT affect sensory structures in the antennae, only an increase in swing duration was observed upon surgical removal of the antenna, arguing that all other phenotypes are a result of knocking out sensory feedback specifically from the legs (data not shown).
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The thresholds for heat and cold perception (QST) showed no statistically significant differences between the operated leg and the unoperated leg (data not shown).
In the lower leg, levels of MMP activity were insignificantly reduced compared with upper leg values, but the differences between patient groups remained similar to findings in the upper leg (data not shown).
We did not find any effects on tendon specification in Stripe>lbRNAi leg discs data not shown.
Although Cdc421 is reported to be an antimorphic allele [14], it does not have a dominant effect on leg morphogenesis (data not shown).
The same pattern with little change in IRRs by these adjustments was seen for sitting height and leg length (data not shown).
The majority of infiltrating lymphocytes were observed at the tumour margin in the interface with healthy leg muscle (data not shown).
There was no significant difference in Hb concentration (Table 4) or in the relationship between Hb and FGF23 in RFU children with or without leg deformities (data not shown).
The mean raw change scores between the "important improvement" and "no change" groups showed a significant difference for all instruments except for SF36 (pf) in leg pain patients and LBPRSdisability in PrS and leg pain patients (data not shown).
Falls were reported to occur most frequently as a result of tripping (44.3 %), slipping (15 %), other (15 %), loss of support/surface structure (10.6 %), knocked over (6.2 %), loss of balance (5.3 %) and legs giving way (3.5 %) (data not shown).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com