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For the final Random Forest model calibration, we combined the legacy sample set with the additional samples.
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Legacy samples are a valuable data source for digital soil mapping.
Further, we tested how precisely available legacy samples cover the variability of the covariates within each potential sampling area to define the final sampling area and to apply a purposive sampling design.
The committee realizes the difficulty of enforcing current rules on such legacy samples.
"If we apply today's standards to all samples, a lot of legacy samples will have to be discarded," says Lim. Hence, old biomaterials from legacy collections--regardless of how they were obtained--may be put to reasonable and respectful use for the greater public good.
High-quality miRNA and mRNA expression data were generated from legacy samples from 115 MM patients treated on E2603.
These data were generated from formalin-fixed paraffin-embedded (FFPE) legacy samples from a phase III multicenter clinical trial that represents a limitation of this study.
If the submitter wishes to use his/her own consent (rather than that of the CMG) or has legacy samples from individuals who cannot be reconsented, the coordinator requests that the consents be uploaded for ELSI committee review.
This study follows a DSM approach using a Random Forest regression model, legacy soil samples, and terrain covariates to estimate topsoil silt and clay contents in a small catchment of 4.2 km2 in the Three Gorges Reservoir Area, Central China.
As legacy soil samples can be inaccurately localized or can be located out of bare soils of hyperspectral airborne data or out of the study area, these data could be unusable as calibration data for classical predictive models (such as the partial least-squares regression method).
Legacy tissue samples--usually small tissues from diagnostics--are stored in liquid nitrogen or paraffin blocks.
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