The SAD patient showed significantly decreased FA values in the white matter of the left insula, left inferior frontal gyrus, left middle temporal gyrus, and left inferior parietal gyrus and increased ADC values in the left insula, bilateral inferior frontal gyrus, bilateral middle temporal gyrus, and left inferior parietal gyrus.
In comparison to the HCs, the SAD patients had decreased FA values in the white matter of the left insula, left inferior frontal gyrus, left middle temporal gyrus, and left inferior parietal gyrus.
It is particularly interesting that all of significantly decreased FA regions occurred in the left hemisphere including the left insula cortex, left inferior frontal gyrus, left inferior parietal gyrus, and left middle temporal gyrus in the SAD patient group.
The frequency of right superior, left superior, and left inferior pulmonary veins involvement is similar.
Further peaks were observed in the left inferior angular gyrus, left inferior frontal gyrus and bilateral medial frontal lobe.
In the controls, both the left inferior frontal gyrus and left inferior parietal lobule, angular gyrus and supramarginal gyrus were activated by the presence of a syntactic ambiguity.
The objects stimulus contrast demonstrated activation clusters in controls overlying the left inferior temporal gyrus, left fusiform gyrus, left inferior and middle occipital gyrus.
All sentences elicited activation in traditional language brain regions including left inferior frontal gyrus, left anterior inferior temporal and left posterior middle temporal gyri.
Unilateral activation was found in the left inferior parietal lobe (IPL), right middle occipital gyrus (MOG) and left inferior frontal gyrus (IFG) (see Figure 2C).
The SAD patients also showed increased ADC values in the left and right inferior frontal gyrus, left and right middle temporal gyrus, left inferior parietal gyrus, and left insula.
The model of Lau and colleagues (2008) also included left inferior parietal lobule, left anterior temporal cortex and the posterior part of left inferior frontal gyrus.
