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The research has left a profound effect on the writer.
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The spirituals and folk singing he heard there left a profound impression on his works.
When Robert, his father, decided to leave, it had a profound effect on the family's fortunes.
They will have a profound effect on the economy, on businesses, and on families".
Our indifference will have a profound effect on future operations.
But voting to leave the European Union could have a profound effect on their welfare.
Since the aged varnish layer had strongly yellowed and gave the painting an inappropriate gloss-the painting was intended to be left unvarnished-, this cleaning treatment had a profound effect on the overall color scheme and appearance of the painting, lifting the brightness of the colors.
The escape had a profound effect on Mohammed: he left in such haste that he didn't pack any of his toys, including, most distressingly, his video-game console.
The war would have a profound effect on the future writer who said: "when I left for that war I dreamed of purification in the fire of battles".
She can understand how Doonreagan House came to have such a profound effect on him: she herself arrived in the summer of 1982 to write a book, and never left.
It had a profound effect on me".
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com