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That report provided a paradigm that still dominates today and has led to the stringent limits on low-dose radiation exposure currently in effect.
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The gang rape of the 23-year-old medical student on a moving bus on 16 December 2012 had triggered intense protests across the country which led to the formation of stringent anti-rape laws.
This multiple testing burden has led to the adoption of stringent significance thresholds in GWAS (Sham and Purcell 2014).
The concerns about perinatal outcomes coupled with litigation pressures have also led to the introduction of stringent measures in most developed countries based on the available evidence [ 13, 14].
Their efforts led to the passage of more stringent regulations to better protect farmworkers, the public, and the environment.
The employment of mercenaries increased the number of desertions and the amount of looting; this in turn led to the need for more stringent discipline in the field.
This has led to the development of more stringent algebraic conditions that some polarity items must meet, e.g., anti-additivity (Zwarts 1998).
Recently, a range of factors led to the development of more stringent bureaucratic procedures, governing the conduct of low-risk population-based health research in the United Kingdom.
However, a range of factors have led to the development of more stringent bureaucratic procedures, governing the conduct of health services and health promotion research in the UK [ 2, 3].
This stringent approach led to the identification of 106 independent expression correlates for the ten risk factors (Table 6), a much reduced number compared to the 1,662 expression traits previously identified by the one-to-one association analysis presented in Table 5.
The lack of stringent quality criteria led to the development of many QSAR models in the past that lacked sufficient validation and reliability to make them adequate for regulatory use.
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