Sentence examples for led to increased efficacy from inspiring English sources

This is reflected by the substantial amount of evidence in which the inhibition of one or more of the downstream protein products (e.g., HO-1, COX-2, HSP70) from these pathways has led to increased efficacy of PDT.

Prolonged contact time and lubricating effectof gel anesthesia leads to increased efficacy and avoids the need for frequent corneal wetting.

However, it is uncertain whether targeting higher blood concentrations leads to increased efficacy of vancomycin and/or risk of nephrotoxicity in elderly patients.

For phase I designs, the traditional assumption that increasing dose will always lead to increasing efficacy, appropriate for cytotoxic agents, is not applicable to novel therapeutics such as in colorectal carcinoma.

A previous study showed that combinational inhibition of Wee1 (MK1775) and Chk1 (MK8776) led to increased in vivo efficacy in neuroblastoma xenografts [ 39], providing additional support for our results.

The recent market meltdown, however, has led to increased skepticism about the efficacy of Adam Smith's invisible hand.

That visit led to increased religious tolerance.

Increasing lemma frequencies led to increased fluency.

Increased progranulin translation led to increased secretion.

Increasing concentration led to increased SNP size.

Under basal conditions the corticosterone-invoked increase in freely mobile GluR2 facilitates recruitment and leads to increased synaptic efficacy.