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This would lead to considerable problems in the interpretation of the results.
However, this method could lead to considerable problems at interpretation, in view of the potential discrepancies between different scales or time points.
The problems led to considerable frustration on Friday as evacuees and state and local officials struggled to cope.
There appear to be a number of dimensions to the problems: a major drought over the preceding few years had led to considerable genuine population movement of pastoralists in search of pastures.
They were used in solving a specific problem: Radical changes of the electricity Tariff System, introduced in Serbia in 2001, led to considerable and lasting annual peak load reductions, making the usual, extrapolating forecasting methods dysfunctional.
This led to considerable public controversy.
Using ASC led to considerable decrease in the particle size.
The debate on whether to boycott or attend the Sochi has led to considerable soul searching.
This led to considerable confusion over just what was being proposed.
Supported by massive European immigration, this growth led to considerable economic and social dislocation.
In particular it led to considerable friction between Glenn and Cpt Alan Shepard.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com