Sentence examples for led to a striking decrease from inspiring English sources

Western blotting showed that knockdown of LRP6 led to a striking decrease in β-catenin protein.

Next, shRNA depletion of PAK1 led to a striking decrease in the anchorage-dependent and -independent growth, migration and invasion ability in ACHN cells that was rescued by either a shRNA-resistant wild-type PAK1 or a PAK1 T423E mutant, but not by a shRNA-resistant PAK1 K299R mutant.

Acute overexpression of PNPLA3 148I led to a striking reduction in lipid droplet content, whereas acute overexpression of PNPLA3 148M had no effect (Fig.  5A C).

In transfected Hela cells expressing exogenous ER-α, the mutation of the Sp site led to a striking reduction in basal activity and reduced the estrogen activation.

We found that RNAi-mediated knockdown of mFAS expression in D. serrata led to a striking reduction in both desiccation resistance and male mating success.

Cc2d1a depletion in murine neurons leads to a striking reduction in dendritic complexity and dendritic spine number.

HVT 1 1 led to a dramatic decrease in lung compliance.

But a few years of exposure to a female village head had led to a striking degree of convergence between goals for sons and daughters.

Fascin and Daam1 coimmunoprecipitated from cell extracts, and silencing of fascin led to a striking loss of Daam1 localization to filopodial shafts, but not tips.

Cortisol, however, led to a striking increase in risk-taking in men, whereas it had no effect on risk-taking behavior in women.

Whereas inhibition of the Hedgehog pathway selectively suppressed sebocyte development, Hedgehog pathway activation led to a striking increase both in size and number of sebaceous glands.