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For one traveler, a goofy photo op on a police motorcycle in Costa Rica led to a stop at the local jail.
The frameshift deletion led to a stop codon at position 159 whereas the nonsense mutation led to a stop codon at position 82 in the FGF5 protein.
If the polymorphism was characterized as "damaging" or it led to a stop codon, the amino acid change was considered to be functional.
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The smashing "victory" over Saddam Hussein in the First Gulf War only led to a stop-and-start conflict now almost two decades old that has proved a catastrophe.
We're halfway through the festival and a "hello" no longer leads to a "stop and chat".
Esposito also put much stock in the paperwork that officers must fill out after each street stop.That form includes numerous check boxes, each describing behavior that might lead to a stop, like "furtive movements" or "actions indicative of casing".
This operation leads to a stop codon in frame with the Gag sequences.
The 81 rare variants included one SNP in the upstream region, one in the 5' UTR, 50 intronic SNPs, 10 synonymous and 16 nonsynonymous coding variants, one frameshift mutation that leads to a stop codon and two SNPs in the 3' UTR.
This mutation leads to a stop of transcription and to a lack of functional protein.
The gene-trap leads to a stop in transcription at this point.
Thus, the codon which leads to a stop codon in frame -1 is favoured.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com