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Mutation of the S463/S465 site to AAVA led to a moderate decrease in TAK1 (ΔN -induced phosphorylation, although it significantly decreased BMPR1B (Q203D)-induced phosphorylation.
However, incubation of the cells with DMOG for 6 h led to a moderate decrease in Rho kinase activity as determined by phosphorylation of the substrate MYPT (myosin phosphatase target protein).
Overexpression of miR-124 or knockdown of iASPP using shRNA both led to a moderate decrease in iASPP mRNA expression in SW480 or HT29 cells), suggesting that iASPP is potentially regulated by miR-124.
Compared with cells with δ-catenin overexpression in the absence of Cuc IIa treatment, Cuc IIa treatment in δ-catenin overexpressing cells led to a moderate decrease in S phase and a slight increase in G2/M population.
This reimbursement restriction has led to a moderate decrease in the number of incident diagnoses and initiation of benzodiazepine use in patients with newly diagnosed anxiety or sleeping disorders in 2009 [ 6].
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Slow microstructural degradation due to the support sintering, evidenced by dilatometry, leads to a moderate decrease in the oxygen fluxes with time.
Prolonged heating leads to a moderate decrease of the particle size of α-LA aggregates, while heating does not affect its electrophoretic mobility.
In general, use of limited drip irrigation regime with 50% of water requirement had significant benefits in terms of saved irrigation water although it leads to a moderate decrease in yield without significant negative impact on the fiber quality parameters.
Combined alanine substitution on those residues leads to a moderate decrease in the transcriptional activity of Nrf2, most likely due to a slight reduction in its nuclear accumulation.
In conclusion, we postulate that severe injury to the chest leads to a moderate decrease of pulmonary function in polytrauma patients with ALI and ARDS.
This candidate gene corresponds to SlMDHAR2 (SGN-U573751), but gene expression profiles here do not support this conclusion, and others have shown that overexpression of SlMDHAR2 in tomato can even lead to a moderate decrease in AsA levels of MG fruits [ 24].
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Justyna Jupowicz-Kozak
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