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BA and BR led cell line drug response experiments.
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Loss of E-cadherin led cells migrate faster along the crypt-villus axis and perturbed cellular differentiation.
This will alter the relative frequencies of the two cell types n 1,n 2 and could lead cell types to adapt to the new frequencies by changing their production.
Ectopic expression of miR-155 induces cell survival but its knockdown leads cell to apoptosis and enhances chemosensitivity.
Importantly, the induction of ATF3 leads cell apoptosis, while signals without ATF3 up-regulation do not cause cell damage [ 27].
Different signals may lead cells to different fates [15], [16].
In reality more than one environmental parameter might lead cells to differentiation [3], [6], [7], [23].
These observations strongly indicate that 4p treatment leads cells to a mitotic catastrophe phenotype [ 39].
30 32 Besides, long-term chromate exposure can also cause cyto-toxicity to lead cells apoptosis.
Activation of the RNA-sensing pattern recognition receptor (PRR) in cancer cells leads to cell death and cytokine expression.
p27kip1 overexpression in human cells leads to cell cycle arrest in G1 phase.
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