It appears that the 3′-OH and dNTP held together by the two Mg2+ ions in the catalytic center may stochastically approach each other to be within such a critically short distance that the p Ka of the 3′-OH is reduced for the proton to leave readily.
As he spoke, his shop in Oyster Bay was painting autumn leaves — readily available and in dirt-cheap abundance — gold for an event.
A wooden puzzle with balancing pieces, a bowl filled with glass pebbles, a container of utensils or stationery items that topples over easily, an indoor plant that drops its leaves readily, a decorative indoor water feature that splashes water, etc. are the sorts of gifts to upset the neat freak.
The information as to why teachers leave is readily available and repeated every year in surveys, yet the powers-that-could do little.
Nevertheless, in terms of the functional characterization of Btn1p, retention of Btn1p at the Golgi would leave it readily available for rapid transport to the vacuole when required in response to pH stress.
When his uncle suggested that he go with him to Kampala to work and raise money for school fees, John-Bosco left Karamoja readily, only to realise life was about to get much worse.
The sense of marriage as a "permanent" institution has been weakened, allowing individuals to consider leaving marriages more readily then they may have in the past.
Falvey and co-workers demonstrated that these leaving groups are readily released from phenacyl esters (247) upon photosensitized electron reduction by light-absorbing amines (sens), provided they possess excited-state oxidation potentials below or equal to −2.2 V. Quantitative yields were reported for various derivatives.
"The big problem with the Western diet," Stephen O'Keefe said, "is that it doesn't feed the gut, only the upper G I. All the food has been processed to be readily absorbed, leaving nothing for the lower G I. But it turns out that one of the keys to health is fermentation in the large intestine".
Under moist atmospheric conditions the ascorbyl radicals readily decay, leaving other radicals, which appear to be formed by interaction of ascorbic acid or ascorbyl radicals with some tissue component.
