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On the other hand, delayed treatment may be more difficult and leave sequelae, regardless of location [ 30].
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The chronic phase is characterized by mucosal wound healing and submucosal fibrosis and by the scarring and deposition of excess muscular tissue, extending through day 14 and eventually leaving sequelae [ 5].
In addition, they are readily transmitted to human beings where they produce a grave and debilitating disease that requires a long and costly antibiotic therapy and that often leaves permanent sequelae [1].
In all three cases in which headaches or weakness of the lower extremities was observed, the complaints were temporary leaving no sequelae.
Migraine is traditionally recognized as a purely episodic disorder that patients are left without sequela [1].
Nasal hemangiomas, distort human physiognomy and leave long lasting psychological sequelae.
Among bacterial causes of meningitis, Streptococcus pneumoniae (the pneumococcus) is associated with the highest case-fatality and is the most likely to leave survivors with permanent sequelae.
At the point of diagnosis, the decline in health is rapid and 10% 20% of treated patients die, often within 24 72 hours after the onset of illness, and 10 15% of survivors are left with neurological sequelae [4], [5].
With conservative management the patient's signs and symptoms resolved spontaneously within five weeks of presentation, leaving no permanent sequelae.
This suffering does not always end with the end of successful treatment, as the disease quite often leaves long-term sequelae.
According to the guidelines, major complications were defined as those that required therapy or prolonged hospitalization, or left permanent adverse sequelae, or death.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com