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Some degree of residue preference was also evident for positions 4, 8 and 9. Positions 3 and 6 showed the least specificity although some small effects were present.
The strongest evidence for these 'counterintuitive' treatment-related effects is in increased ventricular expansion, which has the most sensitivity but least specificity to AD.
In the identification of asymptomatic liver disease the GGTP had the least specificity due to a high false positive rate, while the AP provided the highest specificity.
We found question 5 of the ECQ, pertaining to duration of pain to have the least specificity of all of the questions in the ECQ in all versions, which may partly explain the low sensitivity and specificity we found overall.
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Growth on MSA was also highly specific (79% specificity), while the least specific test was the tube coagulase (human and sheep plasma, 11%and7%7% specificity, respectively).
Other cut-off values included a point with both high sensitivity (over 90%) and at least 30% specificity, and another point with high specificity (over 85%) with at least 20% sensitivity.
Nifedipine exhibited the least pulmonary specificity and was the least effective agent in decreasing pulmonary artery pressure.
Hydralazine demonstrated the least pulmonary specificity and resulted in a large decrease in systemic vascular resistance, with only a moderate decrease in pulmonary artery pressure and resistance.
Cut-off points, sensitivity, area under the curve (AUC) and confidence interval were calculated for each gene respectively based on at least 90% specificity (Figure 3; Table 3).
PGTG_14350 transcript levels showed the least tissue specificity of the ten genes.
Relevant values using the rule-in cut-point (at least 95% specificity) are shown in Table 2.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com