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The DBRD curve had the least slope which implied the slowest increase.In Figure 4, the execution time of routing discovery is also compared.
A saltational event allowed a bumble bee mimic to cross the fitness "valley" and reach an alternative fitness "peak" or at least slope thereof [20], [21].
In early patients, when the likelihood of informative censoring is least, slope of change in functional measures might be appropriate as an end point in a definitive phase III trial where using survival as an endpoint would result in substantially increasing the number of patients and/or length of the trial.
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The depth of burial of Tibito Tephra by subsequent biological activity is greatest on valley floors, least on slope crests, and intermediate on 'erosional' slopes.
We used two-stage regression (least squares slope for each test in each individual over time, then weighted regression model with slope as response variable) to assess association of baseline CSF BDNF concentration with subsequent longitudinal changes of cognitive test performance [15].
Model 2 yielded the least biased slope estimates (−11.8% – −18.7% vs. −12.6% – −49.7%, Table 2) and reasonable coverage of true slope in all the Tmax scenarios despite its bias.
After IAGA meeting in Sopron (Hungry) in 2009, and taking in consideration some previous works as (Joselyn, 1985), and (Curto et al., 2007), more objective criteria to select events were introduced, e.g., at least a slope of 3 nT/min at minimum in 3 of 5 low-latitude stations.
This means that the least squares slope and mean of response are appropriate measures to summarize the corresponding effects.
As a sensitivity analysis, we assigned all models with at least one slope change twice the prior probability of the linear no-threshold model, to see how much this influenced the results.
We analyzed these data with a one-tailed Binomial test with the null hypothesis that an equal number of least squares slopes should be positive and negative.
The species with the least pronounced slopes in the relationship between temperature and the sex ratio produced would be less affected or not affected at all.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com