For such problems, a full probabilistic characterization through the resolution of a PDF equation can be obtained through two levels of approximations: first, mixed ensemble moments have to be approximated to lead to a closed system of equations and, second, the resulting nonlocal equations should be at least partially localized to ensure computational efficiency.
Proteins destined for secretion are at least transiently localized to the ER and could theoretically function during their temporary stay in this organelle.
In contrast, the least peripherally localized lamin-associated OLFR1471 locus did not change its position upon loss of lamin A (χ test: p > 0.05; Fig. 2b).
Thus, several proteins have been found to be exclusively or at least preferentially localized in the ciliary membrane or the ciliary lumen.
These results suggest that both Pkh1 and Pkh2 are at least partially localized to eisosomes, and that Pkh1 but not Pkh2 requires Pil1 for this association.
Immunofluorescent staining of NRP1 and NRP2 showed extensive neointimal staining suggestive that NRP1 and NRP2 were at least partly localized to VSMC.
That is, some evolution is always homogeneous, and the evolution of genes that "coevolved" in the same genome is therefore correlated, at least in localized regions of the tree.
Also, from the 86 E.coli metabolic pathways defined in KEGG, 59 showed at least one enzyme localized and the number of localized enzymes scaled linearly with pathway length (see Figure 1B, R = 0.98).
With EPS, there is intermittent pain or burning discomfort of at least moderate severity, localized to epigastrium and occurs for at least a day per week.
Chronic widespread pain (CWP) is defined by the classification criteria of The American College of Rheumatology from 1990 as pain during at least four of the days of the week lasting for at least three months, localized both over and below the waist, and on both the left and right side of the body, as well as in the back and neck [ 1].
