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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com
least final concentration
Grammar usage guide and real-world examplesUSAGE SUMMARY
The phrase "least final concentration" is not standard in written English and may cause confusion.
It could be used in scientific contexts where one is discussing varying concentrations, but clarity is essential. Example: "In our experiment, we observed the effects of the least final concentration of the solution on the reaction rate."
Science
Table of contents
Usage summary
Human-verified examples
Expert writing tips
Linguistic context
Ludwig's wrap-up
Alternative expressions
FAQs
Human-verified similar examples from authoritative sources
Similar Expressions
60 human-written examples
The purified IgG samples were concentrated using Vivaspin 20 ultrafiltration spin columns (Sartorius, Palaiseau, France) according to the recommended protocol to a final concentration of at least 20 mg/ml and the concentrated IgG were then filter-sterilized using 0.22 µm centrifuge filters (Millipore, Carrigtwohill, Ireland).
Science
Results showed that SEDDS have to be diluted to a final concentration of at least ≤ 40% to guarantee their self-emulsification.
When VDM 11 was applied directly to the bathing solution, its final concentration was at least 7 µ m.
Non-imported proteins were either degraded by addition of proteinase K at a final concentration of at least 100 μg/ml and incubation for 10 min at 0°C or the samples were left untreated.
Science
The mixture was incubated on ice for at least 15 min (sample volume 50 μl, final concentration of myosin 300 pM).
Science
4-OHT (Sigma-Aldrich), diluted in ethanol, was added to the crypt culture medium to a final concentration of 500 nM for at least 12 h.
Science & Research
Yeast cells were fixed by adding formaldehyde to a final concentration of 5% and incubating at least 2 h at room temperature with gentle shaking.
Science
After incubation, trypsin was then inactivated by adding 4- 2-aminoethyl) benzenesulfonyl fluoride hydrochloride (AEBSF) (final concentration = 1 mM) for at least 15 min at room temperature.
Science
Cells were labelled with 3- 4,5-dimethylthiazol-2-yl -2,5-diphenyltetrazolium bromide (MTT) at a final concentration of 0.5 mg/mL for at least 4 h at 3- 4,5-dimethylthiazol-2-yl -2,5-diphenyltetrazolium
Science
Samples preserved with 1% lugol (final concentration) were allowed to settle for at least 24 h in sedimentation chambers (10 cm3), followed by counts at ×200 and ×400 magnification under an inverted microscope (Olympus CKX41, Olympic America, Center Valley, PA).
Science
RNA was precipitated from the aqueous phase by adding sodium acetate to a final concentration of 300 mM followed by at least one volume of isopropanol.
Science
Expert writing Tips
Best practice
When using the phrase "least final concentration", ensure the context is scientifically precise to avoid ambiguity. Clearly define the parameters and units of measurement.
Common error
Don't use "least final concentration" in general contexts where the specific measured value of concentration is not critical. Instead, opt for more descriptive language if exactitude is not required.
Source & Trust
82%
Authority and reliability
3.8/5
Expert rating
Real-world application tested
Linguistic Context
The phrase "least final concentration" functions as a descriptive term specifying the minimum acceptable level of a substance at the conclusion of a process. Ludwig's analysis indicates this term is grammatically acceptable but not widely used.
Frequent in
Science
100%
Less common in
News & Media
0%
Formal & Business
0%
Wiki
0%
Ludwig's WRAP-UP
In summary, "least final concentration" is a phrase used to denote the minimum acceptable amount of a substance at the end of a process, predominantly in scientific contexts. While grammatically acceptable, it is less common than alternatives like ""minimum final concentration"". Ludwig's analysis suggests that this phrase is more prone to ambiguity, and thus should be carefully implemented. When using it, ensure precise definition of parameters and units. Sources like Nature and PlosOne show its usage in scientific research, emphasizing the importance of precision. Although the phrase is understandable, prioritizing clarity with alternative phrasing may be beneficial.
More alternative expressions(10)
Phrases that express similar concepts, ordered by semantic similarity:
minimum final concentration
Replaces "least" with "minimum" to denote the smallest acceptable final concentration.
lowest final concentration
Substitutes "least" with "lowest", indicating the smallest value of final concentration.
smallest final concentration
Replaces "least" with "smallest", specifying the minimal size of the final concentration.
minimum concentration at the end
Rephrases to emphasize that the minimum concentration is at the conclusion of a process.
minimum resulting concentration
Focuses on the minimum concentration obtained as a result.
absolute minimum final concentration
Adds "absolute" to emphasize that there is no concentration smaller than the one specified.
the lowest concentration achieved
Focuses on what has been achieved rather than prescribing a value.
minimum terminal concentration
Uses "terminal" to specify the final concentration is the last one.
threshold final concentration
Emphasizes the boundary or limit of acceptable final concentrations.
critical minimum final concentration
Highlights that the minimum final concentration is crucial or essential.
FAQs
What does "least final concentration" mean in scientific terms?
In a scientific context, "least final concentration" refers to the minimum acceptable amount of a substance present at the end of a process or experiment. It specifies the lower limit of concentration required for the desired outcome.
How can I use "least final concentration" in a sentence?
You might say, "The experiment requires a "minimum final concentration" of 0.1 M to ensure the reaction proceeds efficiently." In this sentence, it explains the minimum concentration required for the experiment.
What's the difference between "least final concentration" and "highest final concentration"?
"Least final concentration" indicates the lowest acceptable level, while "highest final concentration" denotes the maximum permissible level of a substance at the end of a process. They represent opposite ends of a concentration range.
Which is a better term to use, "least final concentration" or ""minimum final concentration""?
"Minimum final concentration" is generally preferred over "least final concentration" due to its clearer and more standard usage in scientific and technical writing. While both are understandable, "minimum" is less ambiguous.
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Table of contents
Usage summary
Human-verified examples
Expert writing tips
Linguistic context
Ludwig's wrap-up
Alternative expressions
FAQs
Source & Trust
82%
Authority and reliability
3.8/5
Expert rating
Real-world application tested