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Non-structural protein 4A (NS4A), one of the least characterized viral proteins, is a highly hydrophobic transmembrane protein thought to induce the membrane alterations that harbor the viral replication complex.
Brk1 is the least characterized subunit of the Wave complex.
Sp2 is the least characterized member of the glutamine-rich subgroup of Sp factors.
The Wave complex is composed of five subunits, the smallest of which, Brick1/Hspc300 (Brk1), is the least characterized.
The last mechanism is the least characterized among the four, mostly due to the great difficulty to obtain primary lymph material.
The various Mur enzymes, as well as Mpl, have most variation in this CD domain (Figure 2), which reflects that they are all likely to have different interactions with the incoming peptide substrate, but this aspect of Mur function remains the least characterized.
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Contrast that with Uber's approach, which, at least as characterized in an interview with Uber founder Travis Kalanick at TechCrunch Disrupt this year, puts that app-based personal transportation service at odds with a lot of local regulatory bodies.
The IL-36 subfamily is the most diverse, including three agonists and one antagonist (IL-36Ra), yet least well characterized group within this family.
The mapping of cell density to signal molecule concentration and the corresponding network modules involved have been at least partially characterized in many bacteria, and vary markedly between different systems.
Therefore, these results (and any future unexpected findings in mice) should at least be characterized in nonhuman primates to assess the extent of damage to the host by ZIKV, and based on experimental data in conjunction with current clinical findings, re-evaluate the real threat posed by ZIKV infections to humans.
As we have seen, there is no commonly accepted, strict definition of singularity, no physically reasonable definition of missing point, and no necessary connection of singular structure, at least as characterized by the presence of incomplete paths, to the presence of curvature pathology.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com