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Taken together, our findings point to generic features of brain aging and provide the prerequisites to model individual aspects of learning dysfunction with insect models.
Targeting the miR-34 seed in APP/PS1-21 mice (were miR-34c is the predominant species) rescued learning dysfunction in mouse models (Zovoilis et al, 2011).
We were interested to evaluate alcohol's effect on GABAAα5 expression to further understand alcohol-induced learning dysfunction.
Traumatic brain injury is associated with permanent spatial learning dysfunction and motor deficits due to brain damage [ 4].
For the Mod-Pb group, succimer treatment almost completely removed Pb from the brain and effectively alleviated the learning dysfunction.
This constellation of findings suggests that succimer treatment of the High-Pb rats reduced tissue (i.e., brain) Pb levels below that which produces lasting impairment in emotion regulation, but not enough to alleviate the learning dysfunction.
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This is of translational value because clinical observations report that general and profound learning dysfunctions do not occur in the early course of AD.
Third lesson learned: the dysfunction of poverty is not about race, it is about class.
Other names for dyspraxia include Clumsy Child Syndrome Developmental Co-ordination Disorderr (DCD); Minimal Brain Dysfunction: Motor learning Difficulty; and Pereceptuo-motor Dysfunction".. Compare your symptoms (or those of your loved one) to the list of symptoms /signs of Dyspraxia.
Learning and memory dysfunction probably occurs secondary to damage to arterioles and dopaminergic neurons by MPTP.
Learning and memory dysfunction by injection of Aβ(1 42) was recovered by administration of these molecules.
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