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In case control metabolic studies, the independent effects of lean vs obese and gestational age/non-pregnant status and their interaction were analysed similarly with post hoc analyses (lean vs obese then gestational age/non-pregnant status in each group).
The Lean vs Fat Startup Debate (link).
In the longitudinal cohort, the independent effects of lean vs very severely obese status and gestational age and their interaction were analysed using two-way repeated ANOVA.
Post hoc analyses determined differences between lean vs very severely obese groups and differences between time points in the obese and then separately in the lean groups.
Fractional extraction of [H5]glycerol from the circulation (lean vs obese, 16.6 ± 4.5 vs 13.9 ± 6.7%) and total glycerol uptake expressed relative to total glycerol release were very small (lean vs obese, 9.7 ± 3.4 vs 9.3 ± 2.5% of total release) with no significant difference between lean and obese participants (p = 0.74 and p = 0.92, respectively).
In those delivering by spontaneous vaginal delivery, instrumentation was necessary in 46% vs 41% and perineal tears/episiotomy was observed/performed in 78%vs76%6% of lean vs very severely obese mothers (both p > 0.05).
Similar(46)
In Experiment 1, eight pigeons responded in a multiple schedule in which the red key was always associated with a VI 90-s schedule and the green key with either a richer (VI 18 s) or leaner (VI 540 s) schedule in different conditions.
In line with these findings, the beta-adrenergically mediated increase in total glycerol release across abdominal SAT was blunted in the obese group [Δ total glycerol release obese vs lean, 140 ± 71 vs 394 ± 112 nmol (100 g tissue)−1 min−1, p < 0.05] (Fig. 2b), suggesting a blunted lipolytic response per unit of abdominal SAT in obese participants.
Patients with the largest TARTs (n=8, volume >1 cm) had similar age and fat mass but higher lean mass (19.5±2.4 vs 16.6 kg/m, P=0.025) and shorter height (162±8 vs 173±6 cm, P=0.011) than those with no or very small TARTs (n=7, volume <0.2 cm).
> -wrap-foot> Varees are mean ± SEM b p < 0.05 baseline obese vs lean; a p < 0.05 change from baseline obese vs lean using unpaired Student's t test In the pilot experiment, the tracer/tracee ratios (TTR) obtained during a 6 h [H5]glycerol infusion after an overnight fast were examined (n = 3).
We tested the hypothesis that the proliferative estrogen effect on the endometrium is enhanced in obese vs lean animals.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com