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Of course he'd got the tan gene and the straight-hair gene and the lean gene, genes that were long dormant in their parents, though pictures proved that they had once been quite the pair.
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Tracing techniques in this class lean on gene expression technology designed to 'label' projections exclusively originating from neurons expressing a very specific molecular phenotype.
Class prediction (obese or lean) from gene expression data was carried out through the WEKA Explorer and WEKA Experimenter applications.
"I've inherited my father's lean Glaswegian genes, but I managed to put on three and a half stone in lean muscle".
In comparison with lean animals, hepatic gene expression of UCP2 is increased in ob/ ob mice and DIO rats [ 11, 12].
Moreover, the expression of several genes involved in metabolic processes was higher in the lean controls, including genes categorized to Fatty acid metabolism, Amino acid metabolism, Carbohydrate metabolism, and Coenzyme and prosthetic group metabolism (Figure 2).
PLS-based MLAS approach was used to detect associations between each gene and lean body mass.
In the analysis, we found a significant association between the PRDM16 gene and lean body mass but not fat mass.
Interestingly, autophagy plays an opposite role in lipid accumulation in adipose tissue and mice with adipose-specific knockout of autophagic ATG7 gene are lean and have decreased white adipose mass and enhanced insulin sensitivity (Singh et al, 2009b; Zhang et al, 2009).
Comparison of classifier performance for predicting obese and lean phenotype with a full (183 genes) or filtered (11 gene) gene inputs Our study demonstrates significant gene expression differences in whole blood from age-matched obese and lean subjects of Northern European White genetic ancestry.
The heavier mice had higher levels of proteins involved in detoxification and stress responses; the lean mice expressed more genes involved in breaking down dietary fiber.
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