Sentence examples for leak channels from inspiring English sources

Passive responses due to the electrical equivalent circuit of the three-dimensional neuron architecture with leak channels were examined first, followed by the responses after adding voltage-gated channels and finally synaptic noise.

Membrane permeability to K+ through K leak channels has been considered as the key conductance to determine the RMP [7].

It would be an interesting objective for future studies to investigate Ca2+ influx, e.g. from leak channels, in aged 'revertants'revertants

This hypothesis is consistent with reports that sanshool activates mechanosensitive neurons via blockade of potassium leak channels [11].

Finally, two open-rectifying leak channels (KCNK5, KCNK10), a sodium channel modulatory subunit (SCN3B), and ANK3, a member of the ankyrin family that can cluster sodium or potassium channels, all shared a lower expression in HVC.

Heterologous expression of ligand-gated receptors and leak channels received initial attention [17], [19], [20], [21], [22], but this approach has largely been supplanted by optogenetic approaches that employ channels directly activated by light [23], [24], [25], [26].

This may account for its lesser gating charge and that it functions as a leak channel when associated with ancillary subunits such as MiRP2.

Nitrergic self-inhibition also has features in common with nitrergic excitation of the MCC in Aplysia [7], in which NO via cGMP closes an outward leak channel, thereby depolarizing the MCC, rather than closing an inward leak channel and thereby polarizing B31/B32.

Recently, it was shown that the unique S4 charge deficit of Kv7.1 compared to other Kv channels underlies its unique conversion to a leak channel by auxiliary subunits such as KCNE3 [18].

Fixing the rate of each leak channel to 25 ions per second per PMCA and 48 ions per second per NCX resulted in a basal dendritic calcium concentration ([Ca2+]i) of 50 nM [5], [55], [56], [57].

Other proteins, such as serine/threonine kinase NLK and sodium leak channel non-selective protein were more abundant in PP MScl than in RR MScl, although for the latter protein the difference was small (1.18 fold increase).