SKP showed that although initially anodes, were established at the defect surrounded by cathode areas, subsequent deposition of corrosion products can sometimes lead to relocation of the anode to beneath the coating.
This disruption of the thiol zinc interaction leads to allosteric relocation of the prodomain leading to active forms of the enzyme with the propeptide still attached or to autoproteolytic removal of the relocated prodomain.
We find that lamin A-associated genes are predominantly transcriptionally silent and that loss of lamin association leads to the relocation of peripherally localized genes, but not necessarily to their activation.
This conformational switch also leads to the relocation of the DNA binding domains, rendering the protein unable to bind the IR1 operator site, thus allowing upregulation of qacA transcription (8).
Phosphorylation of the activation loop (A-loop) is one of the most common mechanisms for regulating protein kinase activity, and it leads to the relocation of an Asp Phe Gly (DFG) motif located adjacent to the N-terminus of the A-loop.
Although this value is insignificant, the upper bound of the 95% confidence interval suggests that a two standard deviation increase in annual homicides per 100,000 inhabitants leads to an increase in relocation, either within or across states, of 0.22%.
Since the reduction in synaptic Homer1b clusters was not accompanied by a change in whole-cell levels of the protein (or its truncated forms), it would appear that Aβ treatment leads to cluster dissociation and relocation to another cellular compartment [cf.34].
One recently proposed scenario suggests that DNA damage and the cellular response to it leads to chromatin defects via relocation of epigenetic machinery from its normal distribution in the genome and to structural chromatin changes, eventually resulting in gene misregulation [ 34].
In 1979 the franchise's financial difficulties led to a relocation to Salt Lake City, where it somewhat incongruously retained the name Jazz.
Enormously successful from the perspective of white Southerners, the policy led to the relocation of 45,690 Indians during the two Jackson administrations.
