Sentence examples for leads identification from inspiring English sources

In this article we intended to review the most important biological effects of thiazole-based compounds and highlight their roles in new leads identification and drug discovery.

Besides the enormous use of PDMs and their derivatives in drug discovery there is still lack of composite repertoire of these natural molecules which can be directly used for prospection of novel leads identification.

Gamo, F. J. et al. Thousands of chemical starting points for antimalarial lead identification.

Fragment-based ligand design is a novel concept for lead identification in drug discovery.

The current drug discovery paradigm allocates a short period of time (3 12 months) for the process of lead identification.

Several technology-based strategies have been developed to address the significance of the two phases of drug discovery: hit identification and lead identification.

While the structures of lead compounds cannot be disclosed, the analysis is thought to provide an example of the interplay of different methods applied in practical lead identification.

Despite tremendous advances in the science and technology of new lead identification and optimization, attrition rates for novel drug candidates making it into the clinic remain unacceptably high.

Heat shock protein 90 inhibitors have huge structural diversity, and here we present the lead identification of novel inhibitors based on β-lactam and imine templates.

Hit triage, following a high-throughput screen for TYK2 inhibitors, revealed pyridine 1 as a promising starting point for lead identification.

Using a biologically relevant peptide or protein structure as a starting point for lead identification represents one of the most powerful approaches in modern drug discovery.