Exact(12)
Agonist stimulation leads cells to regulate integrin affinity ("activation"), thus controlling cell adhesion and migration, controlling extracellular-matrix assembly, and contributing to angiogenesis, tumor cell metastasis, inflammation, the immune response, and hemostasis.
Such pathways often involve the activation of the cell cycle inhibitors, p21CIP1/WAF1 [10]–[12] and p16INK4a [13]–[18], which are likely the genes that act to induce cellular senescence, and are in fact direct targets of the genetic program that leads cells to senescence [19], [20].
These observations strongly indicate that 4p treatment leads cells to a mitotic catastrophe phenotype [ 39].
Signal transduction mediated by ceramide leads cells to produce cytokine induced apoptosis during several inflammatory responses.
The elevated expression of Bax and decreased expression of Bcl-2 leads cells to activate apoptosis to higher levels.
Thus, yeast meiotic initiation is the consequence of systems-level feedback that leads cells into distinct sporulation states.
Similar(48)
Different signals may lead cells to different fates [15], [16].
In reality more than one environmental parameter might lead cells to differentiation [3], [6], [7], [23].
30 32 Besides, long-term chromate exposure can also cause cyto-toxicity to lead cells apoptosis.
This will alter the relative frequencies of the two cell types n 1,n 2 and could lead cell types to adapt to the new frequencies by changing their production.
Adhesion between individual border cells communicates direction from the lead cell to the followers.
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