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The DNA sequence of a repeat and its copy number can evolve rapidly, leading to specificity within a particular species/genome or even a chromosome (Galasso et al. 1995; Wang et al. 1995; Matyasek et al. 1997).
Due to morphological and functional similarities of fungi both with plant cell and human cell, the search for effective targets leading to specificity of antifungal drug action becomes all that more difficult.
Thus, Montastraea spp.-Symbiodinium specificity at the population level appears to be tracking host genetics and morphology, with introgression in the Bahamas breaking down the mechanism(s) leading to specificity and potential co-evolution between the symbiotic partners.
For the comparison, we report positive predictive value instead of specificity as a metric for false positives since the number of true negatives is far larger than the number of false positives, always leading to specificity values greater than 99.9%.
Making this assumption, specific MH plants and also some specific temperate mixotrophic plants (such as Limodorum abortivum [ 38]) would simply go beyond a threshold in terms of C loss for the fungus, thus entering the co-adaptation and/or parasitic co-evolution process leading to specificity.
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Thus, the different response of AtCuAO1 and AtCuAO2 to these compounds, together with the different localization of the corresponding proteins, suggest a divergent evolution of CuAO family members leading to specificities in the response to biotrophic and necrotrophic pathogens.
To reach a specificity of about 0.8, one could either choose a cutoff point of 2.1 leading to a specificity of 0.792 or a cutoff point of 2.2 leading to a specificity of 0.816.
Ecosystems consisted of distinctive plants, e.g., crop plants were limited to anthropogenic systems and most trees only occurred in forests; this is leading to high specificity of AMF for certain ecosystems and distinct ecosystemic composition because of high host specificity of AMF.
However, identifiers for nonpreferred, invalid or even incorrect structures may also be returned leading to reduced specificity.
Where parasites are active, vagile and coupled with hosts whose behavior and ecology brings the parasite into contact with many potential hosts, the likelihood of host switching is increased, usually leading to lowered specificity.
Using this miRNA we classified 35 (89.7%) of the 39 samples correctly, but four samples (9.8%) were misclassified (two MS sera false negatively, and two control sera false positively) leading to a specificity of 89.5%, a sensitivity of 90% and an accuracy of 89.7%.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com