Sentence examples for leading to repression from inspiring English sources

In daf-2 mutants under these conditions, DAF-16 is aberrantly activated, leading to repression of surface-determining genes.

Hfq-dependent sRNAs typically act by binding to the 5'-region of target mRNAs, leading to repression of translation initiation and degradation of the mRNA.

However, the mechanism used by a ligand-bound NR leading to repression of transcription is still a subject of contention [7].

By this strategy, we expected to find mRNAs that interact with LhrA, leading to repression of translation initiation and degradation of the mRNA.

Additionally, Mdm2 mediates histone ubiquitination leading to repression of p53 targets [ 29].

61 However, SIRT1 might facilitate deacetylation and inactivation of p53 in cancerous cells, leading to repression of miR-34a.

Again, a very recent study demonstrated that AhR-mediated gene repression requires combinatorial interactions at E2F-reponsive promoters, leading to the repression of E2F-dependent, S phase-specific genes [ 27].

However, the addition of H2O2 (to iron-starved cells) would lead to the release of iron from iron-sulfur clusters that would interact with Fur, leading to chuABCD repression.

H1 is generally thought to condense chromatin structures, leading to the repression of gene expression44,45.

The concentration of the Cra regulator protein inhibitor, fructose 1,6-bis phosphate), decreases sharply, eventually leading to the repression of transcription.

It would be interesting to investigate whether cGMP suppresses ETR1 by binding to its GAF domain, leading to the repression of ethylene-responsive factors required to establish SAR.