Sir William established links between Latin, Greek and Sanskrit, leading to the concept of 'Indo-European languages' that remains a cornerstone of modern linguistic theory.
Large variations in dissociation distances are found, leading to the concept of a local stacking fault energy (SFE).
Several embedded system applications are used to control physical processes thus leading to the concept of Cyber-Physical System.
The use of US to diagnose the presence of pneumothoraces (PTX) is one such example, leading to the concept of the expanded or EFAST [9, 17].
The increasing availability of geo-referenced data has increased the need to enrich OLAP with spatial analysis, leading to the concept of Spatial OLAP (SOLAP).
Only qualitative prior information on these inputs is used in the design procedure, leading to the concept of quasi-unknown input observers (QUIO).
The first attempt was to extend the notion of a global attractor to the non-autonomous case, leading to the concept of the so-called uniform attractor (see [5]).
In line with this association, moderate intake of antioxidants have shown to reduce the risk of cancer development and slow cancer progression [142 145], leading to the concept that antioxidants can prevent ROS-induced damage and therefore cancer incidence.
In recent years, our knowledge about the pathophysiology of migraine has improved leading to the concept that the disease, typically expressed by episodic manifestations, is, actually, a chronic, and in a subgroup of patients, progressive disorder.
It became evident that the initial systemic inflammatory response syndrome (SIRS) in general exceeds the needs for antimicrobial defense leading to the concept of host-related hyperinflammatory organ dysfunction as a relevant "motor" of developing sepsis [3].
